tag:blogger.com,1999:blog-2878020709809350448.post7192691217538735008..comments2017-11-30T09:35:30.794-05:00Comments on ...And You Will Know Me By The Trail of Papers: Paper trail expansion: odor afterimages in the olfactory bulbMikehttp://www.blogger.com/profile/13460212509225238067noreply@blogger.comBlogger4125tag:blogger.com,1999:blog-2878020709809350448.post-8942368142853859482013-09-20T15:15:09.111-04:002013-09-20T15:15:09.111-04:00That literature is actually quite old and substant...That literature is actually quite old and substantial. <br /><br />http://www.sciencedirect.com/science/article/pii/S0301008296000366#<br /><br />Quote from the .pdf linked above:<br /><br />"In the initial kindling study of Goddard et al.<br />(1969),the amygdala was reported to require the<br />smallest number of stimulations to kindle. Subsequent work has shown that among the limbic Matt Lewishttps://www.blogger.com/profile/09836872275326697874noreply@blogger.comtag:blogger.com,1999:blog-2878020709809350448.post-82688510947823959572013-08-27T04:49:22.528-04:002013-08-27T04:49:22.528-04:00That is a great question. I'm not an expert on...That is a great question. I'm not an expert on epilepsy or seizures, but are there other external signs of seizure? If I remember correctly the mouse was not stiff, but was scrambling with its front legs.<br /><br />Second question, has anyone induced epilepsy or seizures via ChR2? I did a brief Google Scholar search (from home) and didn't see anything. It would actually be kinda Mikehttps://www.blogger.com/profile/13460212509225238067noreply@blogger.comtag:blogger.com,1999:blog-2878020709809350448.post-3933384142969859652013-08-22T17:18:05.471-04:002013-08-22T17:18:05.471-04:00"We did most of these Thy1-ChR2 experiments i..."We did most of these Thy1-ChR2 experiments in anesthetized mice, because in the one awake mouse I stimulated, the mouse started freaking out and drooling. I don't want to know what it smells like when your entire olfactory bulb is activated."<br /><br />How do you know that you are not just inducing a seizure? Drooling is a common response in rodents when seizing. Matt Lewishttps://www.blogger.com/profile/09836872275326697874noreply@blogger.comtag:blogger.com,1999:blog-2878020709809350448.post-89726670091539344222013-08-06T08:17:44.496-04:002013-08-06T08:17:44.496-04:00congrats on the paper! very nice results!congrats on the paper! very nice results!albuddahhttps://www.blogger.com/profile/04112691851820383733noreply@blogger.com